Darolutamide approved for nonmetastatic castration-resistant prostate cancer

Sometimes after finishing prostate cancer treatment, men get an unwelcome surprise: their prostate-specific antigen (PSA) levels creep higher, suggesting tumors too small to be seen lurk somewhere in the body. This leads to several options. Doctors can continue to monitor a man’s condition with imaging scans. Or, given the anxiety associated with rising PSA, they might try to lower the levels with chemically “castrating” drugs that inhibit testosterone, a hormone that makes prostate tumors grow faster. Following that treatment, called androgen deprivation therapy (ADT), PSA generally declines and may become undetectable. But what if PSA climbs further despite ADT’s inhibiting effects on testosterone? This condition is called nonmetastatic, castration-resistant prostate cancer (nmCRPC). It’s called “nonmetastatic” because cancer hasn’t spread in a way that’s detectable with

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Finding Stillness and Gratitude In a Heart Attack

If there is one thing I’ve learned in my journey with Marjorie, it is that life can change in the blink of an eye. No matter how much we plan or perfectly color code our calendars, life happens.And with adversity comes miracles. My family and I are counting our blessings extra this Thanksgiving as we received a miracle that could only be written by God Himself… Sunday morning, I headed off to my beloved homeland of Louisiana for an awesomely busy week of talks, events and fundraisers. I was beyond thrilled to host an Alliance event in Baton Rouge, which would raise funds to create a free clinician led support group in my hometown. My ultimate pay it forward dream and mission was finally happening

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Dental news you’ve missed this week

Missed out on this week’s dental news? No problem, here’s what happened over the past seven days… Labour promises free dental check ups if elected Labour is promising to scrap charges and offer free dental check ups if it wins the next general election. All band one treatment costs will be dropped under the plans, including check ups, scale and polish and X-rays. In addition, Labour says it would fund corrections to fillings, dentures and braces, as well as fluoride varnishes and plastic sealants. The party believes this will cost the NHS £450million a year. The British Dental Association (BDA) has welcomed the move and called on all parties to help improve dental patient access. Adults in England unable to get an NHS dental appointment

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Dangerous bacteria send out warning signals when attacked by antibiotics

A bacterial infection is not just an unpleasant experience – it can also be a major health problem. Some bacteria develop resistance to otherwise effective treatment with antibiotics.

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Higher antibiotic exposure linked to increased risk of Parkinson’s disease

Higher exposure to commonly used oral antibiotics is linked to an increased risk of Parkinson’s disease according to a recently published study by researchers form the Helsinki University Hospital, Finland.

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Samoa climate change resilience challenges Western perceptions

The resilience of Samoan communities in the face of climate change is providing a blueprint for other nations to follow, according to researchers.

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Cochrane review provides information on HPV vaccines and dose schedules in young women, men

New evidence published in the Cochrane Library today provides further information on the benefits and harms of different human papillomavirus vaccines and vaccine schedules in young women and men.

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Libella Gene Therapeutics to Run a Patient Paid Trial of Telomerase Gene Therapy

After Bioviva Science, Libella Gene Therapeutics is the second company to take a run at commercializing telomerase gene therapy treatments for human use. Telomerase is the enzyme responsible for lengthening telomeres, repeated DNA sequences at the ends of chromosomes, though it may have other roles. Telomeres are a part of the mechanism that limits the number of times that a somatic cell can replicate. Telomeres shorten with each cell division, and when too short they trigger programmed cell death or cellular senescence followed by destruction by the immune system. Ordinary somatic cells in humans do not express telomerase; it is only present in stem cells, which can replicate indefinitely to supply tissues with new somatic cells with long telomeres. This split between a small privileged stem cell

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Obesity In Some Kentucky Toddlers On Decline – 89.3 WFPL News Louisville

Obesity In Some Kentucky Toddlers On Decline 89.3 WFPL News Louisville

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Weekly Link Love — Episode 56

Research of the Week Binge drinkers have a lower prefrontal cortical response to alcohol. Implanting fecal matter from people with colon cancer into healthy rodents gives them precancerous lesions. Fecal transplants from people without colon cancer have no such effect. Vegans have more sick days. Creatine may treat depression. New Primal Blueprint Podcasts Episode 390: Rob and Kendra Benson: Host Elle Russ hangs out with Rob and Kendra Benson, owners of Explorado Market, a keto grocery and bakery in Fort Collins, CO and creators of Fat Go Fit, the healthy keto energy packets and jars. Primal Health Coach Radio, Episode 35: Laura and Erin chat with Barbell Physio’s Dr. Zach Long. Each week, select Mark’s Daily Apple blog posts are prepared as Primal Blueprint Podcasts. Need to catch

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Tiny devices made of DNA detect cancer with fewer false alarms

A new cancer-detecting tool uses tiny circuits made of DNA to identify cancer cells by the molecular signature on their surface. The circuits work by attaching to the outside of a cell and analyzing it for proteins that are more abundant on some cell types than others. The devices distinguish cell types with higher specificity than previous methods, giving researchers hope their work could improve diagnosis, or give cancer therapies better aim.

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Some hyper-realistic masks more believable than human faces, study suggests

Researchers asked participants to look at pairs of photographs and decide which showed a normal face and which showed a person wearing a mask. Surprisingly, participants made the wrong call in one in five cases.

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How an AI solution can design new tuberculosis drug regimens

With a shortage of new tuberculosis drugs in the pipeline, a software tool can predict how current drugs–including unlikely candidates – can be combined in new ways to create more effective treatments.

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Wildfires in Oregon’s blue mountains to become more frequent, severe due to climate change

Under a warming climate, wildfires in Oregon’s southern Blue Mountains will become more frequent, more extensive and more severe, according to a new study.

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Five new health and caregiving technologies November 2019

LeadingAge in San Diego and more.  Entrepreneurs clearly see the opportunity for providing tech-enabled services to help care for older adults.  Large events like Leading Age, Argentum, and sub-events within CES and HIMSS all point to the business potential that draws startups as well as new offerings from existing players – in what may become an increasingly crowded market. Here five recent announcements, two from the Startup Garage at Leading Age in San Diego – adding three others from recent press releases.  All information is drawn from the websites of the companies themselves. Curadite. Curadite empowers patients, clinicians, caregivers and family members to work together to improve medication adherence with the support of our intelligently linked, proactive medication management platform. With Curadite’s MMP, healthcare providers and

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Easy Meal Prep: The Ultimate Guide for Healthy, Delicious and Quick Meals

How to prep easy, affordable breakfasts, lunches, and dinners for your week.

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Dogs as a Model of Human Aging

Dogs are an interesting species when it comes to the study of aging. Firstly they are much closer to human metabolism and cellular biochemistry than mice, and secondly selective breeding has generated lineages with a very wide range of sizes and life spans. Thirdly, they occupy a good compromise position in the range of life spans, study cost, and similarity to humans. Mice live short lives, so studies are rapid and comparatively cheap, but there are sizable, important differences between mouse and human biochemistry. Humans live so long that most studies of aging are simply out of the question. Even in non-human primates that live half or less as long as we do, a study of aging and calorie restriction has lasted for decades, and few

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Obesity, other factors may speed up brain aging – Medical Xpress

Obesity, other factors may speed up brain aging Medical Xpress

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AMPED Hydrate: Naturally Better Hydration

Staying hydrated is key to feeling and performing your best, but water isn’t always enough. AMPED Hydrate is a refreshing, natural electrolyte drink that replenishes nutrients lost throughout the day and during exercise. Good hydration is one of the easiest and most effective ways you can support your overall health, but there is more to optimal hydration than water alone. Electrolytes are minerals that perform many essential functions in the body. They control muscle contraction, play a critical role in regulating fluid balance, and help the body absorb water more efficiently (1). Your body loses water and electrolytes throughout the day, especially during exercise or any time you sweat. Drinking water can restore fluids but doesn’t replace depleted electrolytes. Both water and electrolytes are essential for

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Invisalign Pop-Up opens in Westfield, Stratford

Align Technology has launched a new Invisalign Pop-Up, in Westfield Shopping Centre Stratford, east London. It hopes the pop-up experience will re-invent the way consumers interact with the brand. It is a new way of accessing information about teeth straightening and connect with Invisalign doctors in the local area. Fast and convenient Invisalign Pop-Up Patients are increasingly becoming digital-savvy and informed. Indeed, they want to stay in control of their choices and want their experiences to be fast and convenient. The Invisalign Pop-Up therefore taps into these trends by offering an interactive brand activation. ‘It takes them on a digital journey to a new smile,’ Alexandra van der Stap, Align Technology VP consumer marketing, EMEA, said. ‘Our previous

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